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{"slip": { "id": 66, "advice": "Take time once in a while to look up at the stars for at least 5 minutes, in order to comprehend your cosmic significance."}}
{"fact":"A sexually-active feral tom-cat \\owns\\\" an area of about three square miles and \\\"\"sprays\\\"\" to mark his territory with strong smelling urine.\"\"\"","length":145}
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{"slip": { "id": 109, "advice": "To cleanly remove the seed from an Avocado, lay a knife firmly across it, and twist."}}
{"type":"standard","title":"Base excision repair","displaytitle":"Base excision repair","namespace":{"id":0,"text":""},"wikibase_item":"Q3113091","titles":{"canonical":"Base_excision_repair","normalized":"Base excision repair","display":"Base excision repair"},"pageid":2488636,"thumbnail":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/7/72/BER_basic_pathway.svg/330px-BER_basic_pathway.svg.png","width":320,"height":301},"originalimage":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/7/72/BER_basic_pathway.svg/400px-BER_basic_pathway.svg.png","width":400,"height":376},"lang":"en","dir":"ltr","revision":"1269508984","tid":"82c17fda-d2e0-11ef-aed8-41baec48d876","timestamp":"2025-01-15T01:31:58Z","description":"DNA repair process","description_source":"local","content_urls":{"desktop":{"page":"https://en.wikipedia.org/wiki/Base_excision_repair","revisions":"https://en.wikipedia.org/wiki/Base_excision_repair?action=history","edit":"https://en.wikipedia.org/wiki/Base_excision_repair?action=edit","talk":"https://en.wikipedia.org/wiki/Talk:Base_excision_repair"},"mobile":{"page":"https://en.m.wikipedia.org/wiki/Base_excision_repair","revisions":"https://en.m.wikipedia.org/wiki/Special:History/Base_excision_repair","edit":"https://en.m.wikipedia.org/wiki/Base_excision_repair?action=edit","talk":"https://en.m.wikipedia.org/wiki/Talk:Base_excision_repair"}},"extract":"Base excision repair (BER) is a cellular mechanism, studied in the fields of biochemistry and genetics, that repairs damaged DNA throughout the cell cycle. It is responsible primarily for removing small, non-helix-distorting base lesions from the genome. The related nucleotide excision repair pathway repairs bulky helix-distorting lesions. BER is important for removing damaged bases that could otherwise cause mutations by mispairing or lead to breaks in DNA during replication. BER is initiated by DNA glycosylases, which recognize and remove specific damaged or inappropriate bases, forming AP sites. These are then cleaved by an AP endonuclease. The resulting single-strand break can then be processed by either short-patch or long-patch BER.","extract_html":"
Base excision repair (BER) is a cellular mechanism, studied in the fields of biochemistry and genetics, that repairs damaged DNA throughout the cell cycle. It is responsible primarily for removing small, non-helix-distorting base lesions from the genome. The related nucleotide excision repair pathway repairs bulky helix-distorting lesions. BER is important for removing damaged bases that could otherwise cause mutations by mispairing or lead to breaks in DNA during replication. BER is initiated by DNA glycosylases, which recognize and remove specific damaged or inappropriate bases, forming AP sites. These are then cleaved by an AP endonuclease. The resulting single-strand break can then be processed by either short-patch or long-patch BER.
"}